This HPLC method was validated according to the ICH Guideline of Q2 (R1) for linearity, intraday and interday precision and accuracy. (1) HPLC System (Aijiren, Model ) Quaternary pump (Aijiren, Model C) Auto-sampler (Aijiren, Model ) UV detector (Aijiren, Model G1314F) OpenLAB Chromatography Data System (Aijiren, Model CDS)